Metformin
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Metformin - 二甲双胍

Brand Name Drug

Drug Information - 药物信息

Generic Name - 通用名:
Metformin hydrochloride
Brand Name - 品牌名:
Glucophage
Manufacturer - 制造商:
Various
Category - 类别:
Diabetes Medication
FDA Number - FDA编号:
NDA-020357
Dosage - 剂量:
500mg-2000mg daily, taken with meals

⚠️ Warnings - 警告

  • Kidney function monitoring required
  • Risk of lactic acidosis
  • Avoid excessive alcohol
  • May cause vitamin B12 deficiency

Side Effects - 副作用

  • Nausea
  • Diarrhea
  • Stomach upset
  • Metallic taste
  • Lactic acidosis (rare)

Metformin - 二甲双胍

Overview - 概述

Metformin is the most commonly prescribed medication for type 2 diabetes. It belongs to a class of drugs called biguanides and works by reducing glucose production in the liver and improving insulin sensitivity.

二甲双胍是2型糖尿病最常用的处方药。它属于双胍类药物,通过减少肝脏中的葡萄糖产生和改善胰岛素敏感性来发挥作用。

Uses - 用途

  • Type 2 diabetes management - 2型糖尿病管理
  • Blood sugar control - 血糖控制
  • Weight management - 体重管理
  • PCOS treatment - 多囊卵巢综合征治疗

How it works - 作用机理

Metformin works by decreasing hepatic glucose production, decreasing intestinal absorption of glucose, and improving insulin sensitivity by increasing peripheral glucose uptake and utilization.

二甲双胍通过减少肝脏葡萄糖产生、减少肠道葡萄糖吸收,以及通过增加外周葡萄糖摄取和利用来改善胰岛素敏感性。

Important Safety Information - 重要安全信息

Regular kidney function monitoring is essential. Stop taking metformin before certain medical procedures involving contrast dye and restart only after normal kidney function is confirmed.

定期监测肾功能是必要的。在涉及造影剂的某些医疗程序之前停止服用二甲双胍,只有在确认肾功能正常后才重新开始。